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 Article of Interest - Medication

Ritalin is safe - and it works
Research dispels fears that drug hurts kids, and finds that it actually helps brains grow
by Detroit News staff and wire reports
For more articles visit www.bridges4kids.org


NORTHVILLE -- For more than a generation, we've been "drugging" our unruly children to calm them down. And in doing so, we have risked damaging their young brains and setting them up for long-term drug addiction -- or so we have been warned.

But now, that mantra is being turned inside-out. The first long-term results of what some have called a huge drug experiment on our children shows what almost no one expected:

Not only do the stimulant drugs used to treat "attention-deficit-hyperactive disorder" -- or ADHD as it is known -- not damage the brain, they appear to enhance brain growth, helping afflicted children catch up in brain size to their more "normal" peers.

That blockbuster finding, printed recently in the Journal of the American Medical Association, is finally easing the fears of parents afraid of these drugs and is sending experts on a mission to get the word out.

That's good news for parents such as Kathryn Peltier of Northville. She reluctantly allowed her 9-year-old son to take a cocktail of drugs, including Ritalin, after he became so unruly he almost had to be pulled out of school.

"There's always a big trepidation about medicating your child," Peltier said. "As a parent, I held off for as long as I could, but when it comes to your child's well-being versus the risk of medication, then the medication is worth it."

In Michigan, which ranks third in the nation for Ritalin prescriptions, the treatments have generated controversy. Michigan lawmakers this year debated a package of bills that would have have banned teachers from recommending Ritalin or similar psychotropic drugs to students. The bills died in the Senate.

Michigan has consistently remained one of the nation's biggest consumers of Ritalin. During the 1980s, Michigan ranked first nationally in the use of Ritalin and all methamphetamines, but numbers leveled through the 1990s.

Precise numbers weren't available Wednesday, but a 1999 study by the U.S. Drug Enforcement Administration claimed Michigan ranked third behind New Hampshire and Vermont. Nationwide, about 6 million children -- one in eight -- take the medication.

Study ends myths

The popularity of the drug has spurred debate and worry, but West Bloomfield Township family physician Dr. David S. Rosenberg blamed any stigma of Ritalin on drug abusers.

"Ritalin can be a godsend with the right patient, but it can be a curse if it's abused or diverted," he said. "Most diagnoses, though, are appropriate and most patients can see real benefit from the drug."

The 10-year study released by the National Institute of Mental Health seems to echo the sentiment.

Using brain-imaging technology, scientists scanned the brains of some 150 children with attention-deficit-hyperactive disorder while they grew through childhood, comparing them to about the same number of children who didn't have the disorder.

They found that those with the disorder start out with significantly smaller brains -- by 3 percent to 4 percent -- than those without it. And the more severe the disorder, the smaller the brain, the study showed.

But perhaps more crucial, those children who were treated for years with psychostimulants such as Ritalin experienced more brain growth over time than did untreated children, whose brains remained "strikingly smaller" in certain areas.

"There is no evidence that medication harms the brain," said Dr. Xavier Castellanos, the National Institute of Mental Health child psychiatrist who led the study. "It is possible that medication may promote brain maturation."

That likely explains why many students want to and can successfully taper off the medication by the time they reach high school, after years of using it. And that puts to lie another myth -- that these prescribed stimulants set the stage for later addictions to illegal stimulants.

Because these drugs are quickly secreted from the body, many children have required at least three doses a day -- two of them during school hours.

Controversy continues

But that odd phenomenon -- of dozens of kids lining up at the school nurse's office to get their mind-altering drugs -- is changing fast, with today's time-release stimulants. One pill taken at home in the morning can sustain many children through the day.

Not only is the safety of ADHD medications being proven in valid, scientific studies, so also is the effectiveness of them -- notably in yet another decade-long National Institute of Mental Health study, this one comparing treatments in nearly 600 ADHD children.

Just giving psychostimulant drugs alone -- under a doctor's careful and consistent monitoring to achieve the right dose and control side effects -- "normalized" almost twice as many ADHD children, some 56 percent, than did intense behavioral therapy without the drugs, the study found.

However, combining the medication with behavioral therapy achieved the best results -- "normalizing" 68 percent of the ADHD children.

Although these newly emerging studies are reassuring, they by no means have ended the long-simmering nationwide controversy over the medicating of our children.

But that controversy is moving away from dire threats about harmful drugs to warnings that, no matter how good the drugs may be, too many kids getting them don't need them.

Most of the symptoms of ADHD -- fidgeting, squirming, can't stay seated, running around at inappropriate times, can't play quietly, talks too much, won't take turns, can't complete tasks, can't sustain attention or effort -- describe many kids.

There is no doubt that attention-deficit-like symptoms often emerge from other causes -- from child abuse, exposure to too much violence, bipolar disorder, blood sugar imbalances, even food allergies, studies have shown. On such children, stimulant drugs can backfire dangerously, worsening the behavior.

Detroit News Staff Writer Joel Kurth contributed to this report.

 

Ritalin facts

Children diagnosed with attention deficit disorder are usually treated with Ritalin or an amphetamine (primarily Adderall).

Prescriptions for Ritalin and amphetamines have increased five-fold since 1991.

Ritalin prescriptions skyrocketed in the early 1990s, but in recent years have leveled off at 11 million annually.

Since 1996, amphetamine prescriptions have soared to nearly 6 million annually.

Michigan is said to rank average among the states in use of amphetamine prescriptions. No state agency, however, tracks Ritalin or amphetamine use among kids.

Source: Drug Enforcement Administration
 

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